2024 NFL odds Week 6: Lines, spreads for all 14 games

With Week 5 of the NFL season nearly in the books, we’re looking ahead to Week 6. 

Let’s check out the lines for each NFL game at DraftKings Sportsbook as of Oct. 6.

(All times ET)

2024 NFL Week 6 Odds

THURSDAY, OCT. 10

49ERS @ SEAHAWKS (8:15 p.m., Prime Video)

Point spread: 49ers -3 (49ers favored to win by more than 3 points, otherwise Seahawks cover)
Moneyline: 49ers -162 favorites to win (bet $10 to win $16.17 total); Seahawks +136 underdogs to win (bet $10 to win $23.60 total)
Total scoring Over/Under: 47 points scored by both teams combined

San Francisco 49ers

SF

-3.0

-163

O 47.5

Seattle Seahawks

SEA

+3.0

+137

U 47.5

SUNDAY, OCT. 13

JAGUARS @ BEARS (9:30 a.m., NFL Network)

Point spread: Bears -1.5 (Bears favored to win by more than 1.5 points, otherwise Jaguars cover)
Moneyline: Bears -125 favorites to win (bet $10 to win $18 total); Jaguars +105 underdogs to win (bet $10 to win $20.50 total)
Total scoring Over/Under: 43 points scored by both teams combined

Jacksonville Jaguars

JAX

+1.5

+110

O 43

Chicago Bears

CHI

-1.5

-131

U 43

CARDINALS @ PACKERS (1 p.m., FOX/FOX Sports App)

Point spread: Packers -5 (Packers favored to win by more than 5 points, otherwise Cardinals cover)
Moneyline: Packers -230 favorites to win (bet $10 to win $14.35 total); Cardinals +190 underdogs to win (bet $10 to win $29 total)
Total scoring Over/Under: 50 points scored by both teams combined

Arizona Cardinals

ARI

+5.0

+197

O 50

Green Bay Packers

GB

-5.0

-238

U 50

COLTS @ TITANS (1 p.m., CBS)

Point spread: Titans -1 (Titans favored to win by more than 1 point, otherwise Colts cover)
Moneyline: Titans -112 favorites to win (bet $10 to win $18.93 total); Colts -108 underdogs to win (bet $10 to win $19.26 total)
Total scoring Over/Under: 42.5 points scored by both teams combined

Indianapolis Colts

IND

+1.0

-109

O 42.5

Tennessee Titans

TEN

-1.0

-110

U 42.5

TEXANS @ PATRIOTS (1 p.m., CBS)

Point spread: Texans -7 (Texans favored to win by more than 7 points, otherwise Patriots cover)
Moneyline: Texans -345 favorites to win (bet $10 to win $12.90 total); Patriots +275 underdogs to win (bet $10 to win $37.50 total)
Total scoring Over/Under: 38 points scored by both teams combined

Houston Texans

HOU

-7.0

-342

O 37.5

New England Patriots

NE

+7.0

+272

U 37.5

BUCCANEERS @ SAINTS (1 p.m., FOX/FOX Sports App)

Point spread: Saints -2.5 (Saints favored to win by more than 2.5 points, otherwise Buccaneers cover)
Moneyline: Saints -142 favorites to win (bet $10 to win $17.04 total); Buccaneers +120 underdogs to win (bet $10 to win $22 total)
Total scoring Over/Under: 45 points scored by both teams combined

Tampa Bay Buccaneers

TB

+2.5

+122

O 45.5

New Orleans Saints

NO

-2.5

-143

U 45.5

BROWNS @ EAGLES (1 p.m., FOX/FOX Sports App)

Point spread: Eagles -9.5 (Eagles favored to win by more than 9.5 points, otherwise Browns cover)
Moneyline: Eagles -470 favorites to win (bet $10 to win $12.13 total); Browns +360 underdogs to win (bet $10 to win $46 total)
Total scoring Over/Under: 44 points scored by both teams combined

Cleveland Browns

CLE

+8.5

+349

O 44

Philadelphia Eagles

PHI

-8.5

-450

U 44

COMMANDERS @ RAVENS (1 p.m., CBS)

Point spread: Ravens -6.5 (Ravens favored to win by more than 6.5 points, otherwise Commanders cover)
Moneyline: Ravens -278 favorites to win (bet $10 to win $13.60 total); Commanders +225 underdogs to win (bet $10 to win $32.50 total)
Total scoring Over/Under: 52 points scored by both teams combined

Washington Commanders

WAS

+6.5

+233

O 51.5

Baltimore Ravens

BAL

-6.5

-287

U 51.5

CHARGERS @ BRONCOS (4:05 p.m., CBS)

Point spread: Chargers -2.5 (Chargers favored to win by more than 2.5 points, otherwise Broncos cover)
Moneyline: Chargers -135 favorites to win (bet $10 to win $17.04 total); Broncos +120 underdogs to win (bet $10 to win $22 total)
Total scoring Over/Under: 37 points scored by both teams combined

Los Angeles Chargers

LAC

-2.5

-142

O 36.5

Denver Broncos

DEN

+2.5

+120

U 36.5

STEELERS @ RAIDERS (4:05 p.m., CBS)

Point spread: Steelers -3 (Steelers favored to win by more than 3 points, otherwise Raiders cover)
Moneyline: Steelers -162 favorites to win (bet $10 to win $16.17 total); Raiders +136 underdogs to win (bet $10 to win $23.60 total)
Total scoring Over/Under: 37.5 points scored by both teams combined

Pittsburgh Steelers

PIT

-2.5

-175

O 37.5

Las Vegas Raiders

LV

+2.5

+145

U 37.5

LIONS @ COWBOYS (4:25 p.m., FOX/FOX Sports App)

Point spread: Lions -3 (Lions favored to win by more than 3 points, otherwise Cowboys cover)
Moneyline: Lions -155 favorites to win (bet $10 to win $16.45 total); Cowboys +130 underdogs to win (bet $10 to win $23 total)
Total scoring Over/Under: 52fpoints scored by both teams combined

Detroit Lions

DET

-3.0

-155

O 52

Dallas Cowboys

DAL

+3.0

+130

U 52

FALCONS @ PANTHERS (4:25 p.m., FOX/FOX Sports App)

Point spread: Falcons -5 (Falcons favored to win by more than 5 points, otherwise Panthers cover)
Moneyline: Falcons -230 favorites to win (bet $10 to win $14.35 total); Panthers +190 underdogs to win (bet $10 to win $29 total)
Total scoring Over/Under: 48.5 points scored by both teams combined

Atlanta Falcons

ATL

-5.5

-230

O 48.5

Carolina Panthers

CAR

+5.5

+190

U 48.5

BENGALS @ GIANTS (8:20 p.m., NBC/Peacock)

Point spread: Bengals -3.5 (Bengals favored to win by more than 3.5 points, otherwise Giants cover)
Moneyline: Bengals -185 favorites to win (bet $10 to win $15.41 total); Giants +154 underdogs to win (bet $10 to win $25.40 total)
Total scoring Over/Under: 48.5 points scored by both teams combined

Cincinnati Bengals

CIN

-3.5

-184

O 48.5

New York Giants

NYG

+3.5

+154

U 48.5

MONDAY, OCT. 14

BILLS @ JETS (8:15 p.m., ESPN)

Point spread: Bills -2.5 (Bills favored to win by more than 2.5 points, otherwise Jets cover)
Moneyline: Bills -142 favorites to win (bet $10 to win $17.04 total); Jets +120 underdogs to win (bet $10 to win $22 total)
Total scoring Over/Under: 42 points scored by both teams combined

Buffalo Bills

BUF

-2.5

-142

O 41.5

New York Jets

NYJ

+2.5

+120

U 41.5

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